We are lifelong friends, citizens of the world, and passionate about the science behind human longevity and healthspan.
Fivescore Labs exists to deliver longevity protocols as they should be. Protocols that work and delivered by friendly, knowledgeable people who have a passion for living long and healthy lives. That's why we only bring you the most promising molecules that are informed by scientific studies in the fields of human longevity.
Please bear in mind that there are no shortcuts in enhancing healthspan and lifespan. Time and time again, clinical studies have shown that exercise and nutrition are two of the most potent tools we have in our armoury to combat physical and mental decline in older age. Supplementing with evidence backed molecules can be a important strategy in maintaining cellular health but without a holistic long term plan, the benefits of supplementation are stunted.
We are excited to support you on your personal lifespan journey and look forward to serving you with safe and powerful ways to enhance your life for the better. Our vision for Fivescore Labs is to be the leading scientific resource for healthy aging and we can't wait to show you what we have planned.
May you live a long and prosperous life!
Ali, Hani, Leia and Yazan
Founder and Chief Executive Officer
After a 15 year career spent neglecting my health, I underwent a complete transformation when the pandemic hit and took back control of my physical and mental well-being. I shed 16 kgs along the way and got into the best shape of my life. It was around this time that I was drawn to the fascinating world of epigenetics and began adapting my regimen to incorporate lessons that I learnt including optimising my diet (you'd be surprised how harmful the typical 'Western Pattern Diet' actually is), intermittent fasting (who needs breakfast anyway), sleep management (I'm still working on this one) and supplementing with evidence informed exogenous molecules.
It quickly became clear to me that the online market for longevity supplements was replete with fake, untested offerings with little (if any) active ingredients. Alarmingly, a 2021 study in the US showed that almost 65% of NMN supplements available on Amazon contained less than 1% of the stated ingredient. We found this wholly unacceptable and thus Fivescore Labs was born.
Fivescore Labs is the region’s first consumer longevity initiative that is co-founded by scientists and is dedicated to the idea that everyone should have fair access to the science behind human healthspan and lifespan.
Combined with regular exercise, a varied diet, intermittent fasting and quality sleep, as well as a basic understanding of geroscience, there is no reason why we can’t all live healthy, long and productive lives.
I started Fivescore Labs with some of my best friends - Hani, Leia and Yazan - who have dedicated their entire careers to the fields of healthcare, cancer oncology and nuclear medicine. We are super excited by what is in store for the fields of aging and are thrilled to support the human longevity revolution in the region.
I call UAE home and was raised in Saudi Arabia. I am a graduate of McGill University and I have successfully completed a Certificate of Achievement in Genetics and Genomics from the Stanford Center for Professional Development in partnership with the Stanford School of Medicine. In my spare time I enjoy HIIT training, running, weight training and reading up on the latest longevity research. I also hope to live a healthy life to the ripe young age of 120 (fingers crossed!).
Dr. Hani Halabi, MD, MSc
Co-Founder and Scientific Adviser
A passion for care and wanting to make a difference drove me to become a doctor. I left home and my family at 17 and moved to Montreal to study medicine.
After securing my MD from McGill University - Faculty of Medicine, I sought the challenge of caring for cancer patients and that led me to become a radiation oncologist. I completed fellowship training at Harvard Medical school in Boston, before going back as Associate Professor of Radiation Oncology at McGill University.
After years of academic practice, I moved to the United States to join Cancer Treatment Centers of America in Atlanta, part of the City of Hope National Cancer Center. In 2022, I pursued a long-standing ambition of moving back to the region in order to work and live amongst my family and friends.
Having grown up in Saudi Arabia, I am excited to return 'back home' to help lead the region’s longevity revolution. As an oncologist, dealing with the elderly is an important part of my job.
I’ve seen first-hand the impact aging has on patients, their treatment options and overall outcomes. I can tell you from experience that not all octogenarian bodies are the same and I truly believe that age is just a number that can be influenced with the right holistic approach. Prevention is the best medicine, and that is a big part of our ambition in helping you age better. We are on a mission to empower you by providing you with the best tools and protocols allowing you to make optimal life-style choices, in order to stay younger and healthier – both physically and mentally – for longer.
Co-Founder and Chief Operating Officer
Growing up in Canada in a family of healthcare workers, I found an early interest in nursing and eventually pursued a career as an ICU nurse in Montreal. Tending to patients and experiencing the toll that shift work takes on the body allowed me to appreciate the importance of exercise and healthy living to combat the demands of work. I have seen first-hand the timeless benefit of a proactive approach towards healthcare and preventing the onset of aging related decline with a balanced strategy around wellness and mindfulness.
It became very clear to me that maximizing healthspan is critical to living a long and productive life. A passion for fitness led me to become a certified personal trainer in order to deliver the optimal training programs for people with stressful working lives. I also have a bachelors degree in Nursing from McGill University.
My experiences have taught me that proper nutrition is as important as physical exercise in maintaining longevity. I am super excited to share our longevity protocols with you and I hope we are able to help you live the best version of yourself, even if it's in a small way!
Dr. Yazan AlAbed, MD, PhD
Co-Founder and Scientific Adviser
I am a Harvard and McGill University trained physician and scientist. My interest in longevity started during my PhD work on nerve regeneration. I identified key targetable molecular pathways involved in the regeneration of the central nervous system following injury with several patents.
This led to an appreciation of the intrinsic capacity and potential of the human body and cells to repair and reverse damage. As a physician and a scientist, I believe in promoting healthy living by advocating for routine screening for early detection of disease. I also strongly support the use of evidence informed longevity molecules as part of a balanced regimen for helping people achieve a healthier life.
Like Ali and Hani, I grew up in Saudi Arabia as well and call the UAE my home. We are super excited in building Fivescore into a regional champion for human lifespan and healthspan and we hope our project helps you on your own personal journey in achieving your long-term longevity goals.
What’s in a name?
According to the publication American Scientist, in the July 1980 issue of the New England Journal of Medicine, James F. Fries proposed an influential model of health and illness based on the observation that there appear to be, even in the absence of disease, natural limits to the human lifespan.
According to this view, aging is a natural and inevitable part of life. It is marked by a decline in organ function that begins in our 30s and eventually reaches a critical state in which even small perturbations in homeostasis cannot be tolerated.
The benefits of modern medicine, it follows, would be confined to preventing premature death and compressing sickness toward the end of life, not fundamentally prolonging our natural lifespan.
Figure adapted from Fries, 1983, by Tom Dunne.
Historical trends show an increasing limits of mortality rates over the past century, meaning that most people survive to an advanced age, at which point there is a precipitous increase in the number of deaths (green curves). Such data have led some researchers to theorize that the human lifespan is reaching an "ideal" length, beyond which substantial extension is not possible. However, discoveries about the basic mechanisms of aging may permit life expectancy to extend beyond this theoretical limit (red curves).
Fries supported his model with a set of curves that plot survival against age over the 20th century (as shown in the graph above).
As the curves show, improvements in medicine and public health have increased average life expectancy at birth enormously (close to 30 years), whereas the life expectancy of an 80-year-old has hardly increased at all (about two years).
This limitation of the life expectancy function lends support to Fries' concept of fundamental limits on the human lifespan, and suggests that—at least for richer segments of the population—life expectancy is approaching those limits.
Therefore, according to Fries, in the future we should expect diminishing returns in mortality gains for new treatments of infectious diseases, cardiovascular diseases, cancer and the like.
Medical innovation, he argued, should concentrate instead on living better, by "compressing" morbidity to the very end of life, not on living longer.
However, discoveries in more basic sciences, such as our developing understanding of sirtuin activators, suggest that this model may be at least half wrong.
There may be natural limits to the mortality gains we should expect from disease-specific therapies, as Fries suggested. But by influencing the basic mechanisms underlying aging, medical innovations of the 21st century may yet increase the human lifespan in ways he did not foresee.
Indeed, since the remaining frontier for mortality reduction is largely at the end of life, aging itself will have to be addressed and the shape of progress must be altered if there are to be any mortality gains from our huge investment in medical science and technology.
Thus, a new set of curves, extending life expectancy beyond the frontier at the far right of the survival function, could well describe gains in life expectancy in the coming 100 years.
At Fivescore Labs, we do not believe there should be a limit to the human body’s potential to live healthy lives past 100 years of age.
In fact, today only 0.004% of the world’s population is 100 years old. We believe this number is far too low.
If you exercise regularly, eat a varied diet, restrict calorie intake and supplement with pure longevity molecules, we believe 100 years old should be the minimum target and well within reach for the majority of people. Indeed, scientists believe that only about 20% of our health in old age is genetically inherited, the rest is up to us.
With on-going progress in the field of longevity, the human age is fast becoming truly just a number that can be moved back and forth. Modern science is evolving at a rapid pace, and we can barely keep up with the developments.
If for every chronological year that passes you were able to turn your biological clock back by one year, you should in theory live for a very long time indeed.
There are things you can do right now that are scientifically understood to get you to live longer and healthier lives. The key as always is consistency over the long-term in applying the following principles:
Follow an active lifestyle with regular exercise – you don’t need to be an ultra-marathon endurance athlete. In fact, science has shown that 1-hour strenuous exercise sessions 3-4 times a week is enough to activate the human longevity genes.
Make sure to follow a varied and healthy diet – Yes that’s right, we don’t think you need to be a scientist to know that eating hamburgers, chicken shawarmas and pizzas every day won’t get you very far in life.
Don’t smoke – this one is a bit of a no-brainer.
Calorie restriction – intermittent fasting is an incredible way to manage weight, simplify your daily life, activate your longevity genes over the long run, and balance your monthly budgets! What’s there not to love?
Supplement with pure, science backed molecules – if you follow the above 4 steps consistently, scientists believe that supplementing with pure longevity molecules such as NMN and Resveratrol allows your body to perform at optimal cellular levels.
If you were a character in Shakespeare’s Macbeth, you were considered to have done very well for yourself had you lived to the age of “three score” - which means 60 years old (a ‘score’ is twenty years in old Elizabethan English).
We firmly believe that everyone has a fair chance to live to a healthy 100 years – and thus “five score” was born.
Making sure we have a minimal impact on the environment is at the heart and centre of our ethos at Fivescore Labs. After all, what is the point of living longer if we don’t have a world to call a home!
We have partnered with our manufacturer to ensure that the packaging for our supplement bottles are entirely biodegradable.
The base material for our bottles is a vegetal-origin polymer extracted from starch and sugar cane. This raw material is sourced from excess sugar capacity in developing countries across South-East Asia, helping local farmers in rural areas with more stable sugar prices
The carbon footprint for manufacturing our bottles is over 75% lower than the carbon footprint of conventional plastic bottles and a whopping 90% less than that of glass bottles. We think it is important that every Company does their part in helping the environment and we are no different in this regard.